Beyond its dominant role in oncology, Immunohistochemistry is a powerful technique for studying and diagnosing Neurological Disorders. In neuroscience, the method is critical for mapping the expression and distribution of specific proteins and cellular markers within brain and nerve tissue. This is essential for understanding the molecular pathology of complex neurodegenerative conditions like Alzheimer's disease and Parkinson's disease.

For example, IHC is used to visualize the characteristic plaques and tangles associated with Alzheimer's, such as the accumulation of amyloid-beta and hyperphosphorylated tau proteins. Similarly, in Parkinson's research, it can detect the pathological aggregation of alpha-synuclein within neurons. By enabling the precise localization of these disease-specific proteins, IHC provides vital structural and molecular insights that aid in confirming diagnosis post-mortem, studying disease progression, and validating targets for new therapeutic interventions in this challenging area of medicine.

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